Champions League Betting Predictions | Matchday 1

Who wins the 2021/22 Champions League? Read our betting predictions here…

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Who wins this season's Champions League?

Can Man City and Liverpool get off the mark at the first time of asking tonight?

The two Premier League sides will be eager to make the most of home advantage as they begin their European campaigns against RB Leipzig and AC Milan respectively, while Group D also serves up a heavyweight opener as Inter vs Real Madrid tops the bill elsewhere on the continent.

We’re back with our latest Champions League predictions…

Champions League betting

Champions League Betting Tips | Wednesday 15th September

Patience is a virtue.

Before any thoughts turn to Messi vs Guardiola in matchday two, Man City will be looking to get their these 2021/22 Champions League campaign off to a convincing start against a lively RB Leipzig.


Group A Betting

After just falling short last season, can Man City draw a line under their Champions League Final disappointment with a lively start against RB Leipzig on Matchday 1?

The hosts are 3/10 to claim a vital opening day win against a side they have never previously met in European competition before attention switches to that mouthwatering trip to Paris.

Guardiola’s men will be looking to inflict further woe on new RB Leipzig boss Jesse Marsch, with the American losing three of his first four games in charge of last season’s Bundesliga runners-up.

After an extraordinary power play in the transfer market this summer, PSG boss Mauricio Pochettino is a man under serious pressure to finally bring back the Champions League trophy back to Paris.

The French giants make the short trip to Belgium on Wednesday night to take on rank outsiders Club Brugge.

The Belgian Pro League champions more than held their own in last season’s group stages despite failing to advance, picking up eight points from their six matches to claim a Europa League berth and are 7/2 to avoid defeat against Poch’s men on home turf. 

Group A Winner Odds

  • PSG – Evens
  • Man City – 5/4
  • RB Leipzig – 11/2
  • Club Brugge – 100/1

Group B Betting

Can Liverpool rediscover their air of invincibility in the Champions League this season?

An injury-ravaged campaign last year ultimately put paid to any hopes of them retaining the trophy they won in 2019/20 as they exited at the quarter-final stage to Real Madrid, and Jürgen Klopp will need his side back to their imperious best to escape one of the tougher groups in this year’s tournament.  

The Reds have home advantage in Matchday 1 as they take on a Milan side mixing it back with the elite for the first time since 2014.

This fixture is the ultimate nostalgia trip for Reds fans, bringing back happy memories of the club’s miracle comeback win in the 2005 final in Istanbul, and less happy ones too (the 2-1 final defeat two years later) – with that 2007 meeting the last time the two clubs actually traded blows in competitive action.

It’s 59/100 for Klopp’s men to bank an important three points before their upcoming trips to Porto and Madrid.

After La Liga success in 2020/21, Diego Simeone will surely have one eye on claiming the only major prize that has still eluded him as Atlético Madrid boss.

His charges were unusually subdued when limping out at the Round of 16 stage 3-0 on aggregate last season and will be keen not to slip up against a Porto side that performed smartly in the group stages in 2020/21.

Atléti to win by one goal at 43/20 could be the value here with the visitors likely to keep things tight at the Wanda Metropolitano.

Group B Winner Odds

  • Liverpool – 11/10
  • Atlético Madrid – 21/10
  • Milan – 4/1
  • Porto – 8/1

Group C Betting

The relentless Erling Haaland looks set to be the difference maker for Borussia Dortmund in a Group C that otherwise looks wide open.

If, as seems likely with a rumoured €75m contract clause kicking in soon, this is the Norwegian ace’s last season in the yellow and black, Dortmund may just fancy their chances of being wildcards in this competition.

The 21-year-old has already netted eight goals in six appearances this season and could torment group outsiders Beşiktaş as his side travel to Turkey for the 17:45 kick-off. Borussia are 61/50 to score in both halves in Istanbul.

Ajax are back in the group stages of this competition for a fourth season running with the aim of avoiding another early exit into the Europa League having been outflanked by Liverpool and Atalanta in Group D last year.

The Dutch giants travel to Lisbon in Matchday 1 to test the resolve of a Sporting side with designs on advancing past this stage of the competition for the first time since 2009.

The reigning Portuguese champions have drawn both of their last two Primeira games and the stalemate could be value here too at 66/25.

Group C Winner Odds

  • Borussia Dortmund – 3/5
  • Ajax – 69/20
  • Sporting Lisbon – 5/1
  • Beşiktaş – 11/1

Group D Betting

Can arguably the smallest team to ever reach this stage of the competition bring some order to Group D?

Moldovan minnows Sheriff have an early chance to stamp their authority on this group as they welcome Shakhtar Donetsk to Tiraspol in one of Wednesday’s two early-kick offs.

It took a fairy-tale run in qualifying for the national champions to seal their spot in the tournament proper, one capped off by a 3-0 aggregate win over experienced European operators Dinamo Zagreb, but that performance will give them confidence they can get off to an arresting start against their Ukrainian opponents.

Shakhtar will be looking to end a run of three straight third-place finishes in the group stages, but may have to settle for a crack at the Europa League with Inter and Real Madrid likely to be slugging it out for top spot in Group D.

The pair square off at the San Siro in Matchday 1, with the hosts looking to make amends for the two group stage defeats against Real that contributed to their early exit from this competition last season.

It’s 37/25 for the Italians to get some overdue revenge with victory here.

Group D Winner Odds

  • Real Madrid – 19/50
  • Inter – 13/5
  • Shakhtar Donetsk – 12/1
  • Sheriff – 300/1

Champions League - Chance of Winning

Champions League Outright Betting

Check the latest Champions League odds with Marathonbet as Chelsea begin the defence of their title.

The Blues were arguably surprise winners in 2021 as Thomas Tuchel turned their season round at the halfway point to help land the West London club only a second UCL title.

They start as 8/1 shots to do something only Real Madrid have managed in the last 30 years – defend their trophy.

After falling at the final hurdle last year, Pep Guardiola will be more determined than ever to finally guide Man City to a first-ever Champions League title, with European silverware the one thing still to elude the Spaniard since his arrival in English football back in 2016.

The reigning EPL champions are 37/10 to put that right in 2021/22.

Champions League outrights

How will Bayern Munich fare under the ambitious Julian Nagelsmann? At 34 years of age, he would become the youngest Champions League-winning manager in history if he can repeat the German giants’ feat of seizing this title two seasons ago.

He’s 69/10 to make some history in this year’s competition.

Can Liverpool return to the top table after limping out at the quarter-final stage last season? The Reds surely won’t be as unlucky with injuries this time around and are 10/1 to reign supreme again in Europe.

Finally, could it be Poch’s turn to pounce and deliver PSG a first-ever Champions League title?

His side certainly aren’t messing around after stumbling at the semi-final stage in 2020/21.

The French high rollers have had the best summer of any club so far in the transfer market after the free transfer captures of Lionel Messi, Sergio Ramos, Georginio Wijnaldum and Gianluigi Donnarumma.

The Ligue 1 giants are now 37/10 joint favourites to triumph in St Petersburg next summer.


Champions League Outright Winner | Latest Odds

  • PSG – 37/10
  • MAN CITY – 37/10
  • BAYERN MUNICH – 69/10
  • CHELSEA – 8/1
  • LIVERPOOL – 10/1
  • MAN UTD – 21/2
  • REAL MADRID – 15/1
  • BARCELONA – 23/1
  • JUVENTUS – 24/1
  • ATLÉTICO MADRID – 24/1
  • BORUSSIA DORTMUND – 34/1
  • INTER MILAN – 55/1

Information and odds correct at time of writing; fixture dates and venues may be subject to change.

⚽️ Check out our Premier League betting predictions >> ⚽️

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